Characteristic features of Colchicum are the states of paralytic weakness that accompany the pains; the symptoms in the digestive tract that occur with or before the pains; and the tendency of the pains to ‘wander’. One joint after the other is affected, often without redness and sometimes even without swelling.
Hering accentuates a tendency from left to right, which is supported by a proving symptom: ‘Pressive drawing pain in whole left big toe, afterwards same in the right one…’ The small joints are affected comparatively often, e.g. wrists and ankles, finger and toe joints. If, in addition, aggravation from motion and touch is present Colchicum is probably indicated.
A classic description by Gerstel: ‘Before the tearing pains begin, or simultaneously with them, a paralytic sensation of the affected parts sets in, often with general lassitude and weakness… The muscles of the upper and lower limbs feel weary and weak, a sensation which is most marked on motion.
Only with difficulty are the patients able to hold a thing, even if it is very light; they have problems to lift their feet in order to go upstairs, or they stumble over a threshold; their gait is uncertain, and they tend to stumble. When sitting, they have difficulties to stand up; in the morning, they have problems to get up from bed.
‘This state goes along with loss of appetite, thirst and restless sleep because of the uneasiness in the limbs. Later on, the extremity complaints become more marked; the joints become sensitive to pressure, now this joint, now the other, they swell but don’t become red… A peculiarity is that gastric complaints sometimes precede the rheumatism and nearly always accompany it’.