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Materia Medica Viva Volume 6 – page 1258

Such conditions can be encountered in progressed stages of cancer of the stomach, in acute exacerbation of duodenal ulcers, or in severe acute diseases. The patient is excessively irritable or easily irritated and this irritability has a repercussion on his stomach pains. The patient is aware, though, that being vexed or irritated aggravates all his symptoms and so tries to avoid any disturbance that might provoke these states of mind.
Clarke states that Cadmium sulphuratum is a cross between Bryonia and Arsenicum: It has the desire to keep quiet and the complete aversion to motion of Bry., with the exhaustion and stomach irritability of Ars. In my perception there is no way to confuse it with Ars. or Bry. as there are clear differential points. As opposed to Bry., there is usually no great thirst, only a desire for small, infrequent sips which the patient vomits immediately.
Though the patient has a horror of solitude, cannot stay alone and wants somebody with him, he differs from Ars. in that he does not like it if the doctor or someone else comes near him to ‘burden him’, i.e., to demand something from him or to discuss with him. He is too tired and prostrated to communicate. The impression one gets of the patient is also distinguished from Ars. in that he stays quiet, does not want to be disturbed, and in that there is little or no fear of death, even if the patient is obviously going to die.
In addition, in Cadmium sulphuratum, it is the idea of malignancy that prevails. This idea comes immediately to your attention: the black vomit, the chill, the extreme prostration, the horror of solitude and the desire to be left quiet so as to be able to die in peace. All this shows that the patient is really going towards death. These symptoms unite to create a case that is unique and one that demands Cadmium sulphuratum.
Generalities
The action of this remedy is primarily upon the mucous membranes of the stomach, and the digestive system in general; the eyes and