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Essence of Materia Medica – page 136

The Ignatia patient frequently feels constricted in the throat or in breathing, especially following an emotional shock. The characteristic Ignatia sighing is an attempt to relieve this sensation of constriction. Ignatia cries more easily and is more likely to cry during the homoeopathic interview than Natrum mur. Following a grief, the Ignatia patient is less likely to experience sleeplessness than Natrum mur.
Frequently, particularly when there are mostly physical symptoms, Phosphorus may be difficult to differentiate from Natrum mur. Physically, both look quite similar—thin, sensitive, even per¬haps hyperthyroid. The main point of differentiation, of course, is whether the patient has a personality which is closed or open. The sensitive person who tends to be more withheld and evasive, who leans back in the chair while describing symptoms, is more likely to need Natrum mur. The Phosphorus patient, on the other hand, is very open and expressive of emotion, tending to lean forward and engage the interviewer in personal contact.
Lilium tig. is a highly hysterical remedy, as is Natrum mur. If a Lilium tig. patient experiences rejection or humiliation, however, there is an instantaneous, impulsive reaction; the Natrum mur. patient on the other hand, will suffer inside and wait quite a long time before finally breaking down into a hysterical reaction. Lilium tig. is also more likely to be malicious and cruel during such a reaction, whereas the Natrum mur. person would rather inflict suffering on himself than cause pain to anyone else.
Moschus is another hysterical remedy, but the diffenentiation is quite easy. This type of hysteria is designed for others to observe. It is manipulative, an attempt to emotionally blackmail others into a desired response. Natrum mur. would rather hide any reaction as much as possible.
Pulsatilla is sometimes confused with Natrum mur. Both are intolerant to heat aggravated in the sun, and averse to fat. Pulsatilla, however, is emotionally highly expressive, automatically giving affection. When a Pulsatilla patient cries (which occurs easily), it is a "sweet" gentle crying, whereas the Natrum mur. weeping is a spasmodic, loud sobbing which shakes the whole body. Pulsatilla patients that are suffering will actively seek help from others and depend on them; Natrum mur. is more self-reliant, pref¬erring to solve problems by themselves.