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Materia Medica Viva Volume 5 – page 1171

Bryonia headache patients prefer a semi-dark room. Were one to enter the room and turn on a light, their headache would be aggravated, and they would quite probably shout at the person in irritation. Just the small motion of the pupils of the eyes as they accommodate to the change in lighting can provoke an aggravation.
There is another characteristic of Bryonia headaches; they are usually left-sided headaches and are typically situated over the left eye. Spigelia is another principal remedy for headaches in this location; Bryonia, however, is the only remedy corresponding to such headaches which then extend to the left occiput and subsequently to the entire head.
Bursting, splitting or heavy crushing headache, as if everything would be pressed out of the head.
Headache in the morning as soon as the eyes are open and moving the eyes is very painful with twitching and drawing in the malar and maxillary bones. Pain in the forehead, above the left eye, followed by a dull, pressive pain, going to the occiput and thence spreading to the whole body; after eating or moving quickly the pain is so severe that it seems a distinct pulsation in the head; worse while walking, ameliorated by pressure and lying on the left side. Headache after washing with cold water when the face was sweating; even opening the eyelids increases the headache. In the morning before breakfast, pain as if the head were compressed, with heaviness in it mingled with stitches; inability to raise the eyes on account of the pain, and if the patient stoops he cannot rise up.
The headaches begin in the morning and cease towards the evening an d occur after over¬eating or drinking, with constipation or after annoyance from lifting; from suppression of the menses; after anger, rheumatic headache in cold, raw, wet seasons; from running, after scarlatina, in the summer or from exposure to the sun; from the cold, cold wind, or cold, damp weather; during pregnancy or after nursing a baby; from stepping too heavily; on ascending steps.
Meningitis; apoplexy. Convulsions where the aura begins with a jerking in the nape of the neck.
Great fullness and heaviness of the head as if it would fall to either side.