Just like many other gynaecological diseases, Infertility is also one such condition where homoeopathy has shown its efficacy. The present case report is to highlight the positive result of the specific treatment adopted for a 26 years female who was unable to conceive for 2 years despite of trying with several available methods. The most probable cause of infertility in this case was polycystic ovarian syndrome (diagnosed clinically and radiologically). After methodical case taking and analysis of symptoms (both miasmatic and reportorial) Calc carb 1M was prescribed subsequently and ultimately after 11 months patient conceived and final ultrasonography also emphasized on the ovaries which were devoid of any abnormality now.