Positive Research

An Exploratory Study of Autonomic Function Investigations in Hemophiliacs on Homoeopathy Medications Using Impedance Plethysmography

Authors

Tapas K. Kundu, BHMS, Pradip B. Barde, MD, Ghanshyam D. Jindal, PhD, Farooq F. Motiwala, MD

Journal

Journal of Evidence-Based Complementary and Alternative Medicine:2017 Oct; 22(4): 760–764. Published online 2017 Jul 18. doi: 10.1177/2156587217718750

Abstract

Background
Status of autonomic homoeostasis in hemostasic disturbances due to hemophilia needs to be studied.

Objectives.
To compare autonomic nervous system markers measured by heart rate variability (HRV) and blood flow variability (BFV) in hemophiliacs and healthy age-matched control population using medical analyzer system.

Design
Cross-sectional study.

Settings.
Motiwala Homoeopathy Medical College, and Hemophilia Clinics, Nashik.

Subjects
Eighty subjects.

Interventions.
Nil

Outcome measures
Autonomic function markers for HRV and BFV.

Results
Among 80 subjects, BFV time domain measure, root mean square of successive NN (normal-to-normal) interval differences (RMSSD), was significantly higher among hemophiliacs than nonhemophiliacs. Frequency domain analysis parameter, low frequency for both HRV and BFV was significantly higher among hemophiliacs as compared with nonhemophiliacs.

Conclusions
Hemophiliacs were shown to have higher autonomic activity as compared with healthy controls. Homoeopathic medicines used as an adjunct was associated with decrease in parasympathetic modulations.

Keywords
hemophilia, homeopathic, autonomic control

External URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871298/